Generic top-level domain.
Sorry, nerdy domain name lingo. :-)
It doesn't, and .com/.net/.org does not imply American hosting or origin. That's very old thinking; those GTLDs have been geographically non-specific for many years.
In fact there is a .us namespace, but it's not commonly used.
Anyone serious about being found by Internet searches will employ SEO (search engine optimisation) techniques and not rely on namespace to be the defining criterion leading to hits. Namespace tells you nothing.
Take RedBubble. It is an Australian, Melbourne-based company, yet its domain name is redbubble.com.
Well, I've sold images, but I don't run a business.