Get a good flash with ETTL to put on top of your camera. (from AP site sponsor ... http://www.protog.com.au/buy/yongnuo...-camera/YN568C) Bounce the wonderful extra light off the ceiling or wall to get a more even light.
That wonderful extra light will get you to a higher f/# for DOF and keep the ISO down a little. The ETTL lets the camera and flash figure a lot of the equation out for you.
For noise reduction, this software probably works better than DPP ... http://www.imagenomic.com/download.aspx The download at the bottom (Community Edition) is free.